Subject: Almost all calico cats are female.
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Posted on: 2018-05-12 14:04:00 UTC
The black and orange color genes in cats are linked to the X-chromosome. In each cell, one of each matching pair of chromosomes is inactivated, so in calicos and tortoiseshells, you get patches of a different color depending on which X is active. This pattern is only possible in cats with two X-chromosomes, ergo, almost all girls. {= D
It doesn't actually surprise me that most people don't know this, but it DID surprise me when an episode of Star Trek: TNG insisted a tortie was male. It CAN happen, if you get an XXY cat for instance, but it's very rare. I kinda ranted about it. Phobos was not impressed. >.>;
Further reading: X-inactivation.
~Neshomeh